2023 Virtual Meeting

ECCR Virtual Annual Meeting 2023

Was held on Friday 24 – Saturday 25 November 2023

 

Friday, November 24th (All times are CEST/CET)

09:00-09:30       Welcome and Opening – Carmine Savoia, ECCR president (Italy)

09:30-11:00       Session 1

Chairs: Matthias Barton (Switzerland), Muscha Steckelings (Denmark)

(in each talk + 30 min general discussion) 

• Cardiorenal Protective Effects of Combining SGLT2 Inhibition, Endothelin Receptor Antagonism and RAS Blockade in Type 2 Diabetic Mice. Ander Vergara (Spain).
• Obesity and cardiovascular disease: mechanisms and therapeutic solutions. Massimo Volpe (Italy).
• Angiotensin-(1-5): A new hormone within the RAAS? Muscha Steckelings (Denmark).

Discussion

11:00-12:30       Abstract session 1: Presentations of selected abstracts

9 ABSTRACTS (8 min presentation + 2 Discussion)

Chairs: Ana M Briones (Spain), Marko Poglitsch (Austria)

11:00-11:10 –     A.F. Rodrigues: Brain Local Angiotensin II Production Relies on Renin Activity.

11:10-11.20 –     Beatriz Delgado-Valero: Let-7f-5p mediates galectin-3 renal deleterious effects through endoplasmic reticulum stress activation in obese rats with myocardial infarction.

11:20-11:30 – Sthéfanie Chaves de Almeida Gonçalves: Angiotensin-(1-7) protective effect on anxiety and depression-like behaviors in asthmatic mice.

11:30-11:40 – Federico Bernardo Rossi: The Water and electrolytes content in salt-dependent human HYpertension in the SKIn (WHYSKI) before and after surgical cure of primary aldosteronism.

11:40-11:50 – Igor Maciel Souza-Silva; Phosphoproteomics analysis reveals that angiotensin-(1-5) inhibits the mTOR signalling pathway in endothelial cells associated with anti-senescence effects.

11:50-12:00 – May Fayad: Role of the mineralocorticoid receptor in the physiology of the adrenal cortex and the development of aldosterone producing adenomas.

12:00-12:10 – Oliver Thomas: An analysis of sodium intake throughout adulthood on later-life cognition.

12:10-12:20 – Sahar Samanbar: Angiotensin Type 2 Receptor (AT2R) stimulation reduces blood pressure and reverses endothelial dysfunction in a model of diet-induced obesity in mice.

12:20-12:30- Samuel Adu: Palmitoylation of NADPH Oxidase (Nox5) as a potential post-translational regulatory process

12:30-13:30                       Interlude

13:30-15:00                       Session 2

Chairs: Michael Bader (Germany), Gian Paolo Rossi (Italy),

(20 min each talk + 30 min general discussion)

• Aging impairs neurovascular interface in the heart. Stefanie Dimmeler (Germany).
• Sleep disturbance in cardiac disease: role of immune-mediated denervation of the pineal gland. Stefan Engelhardt (Germany).
• Mechanisms of Autophagy in Cardiomyopathy. Junichi Sadoshima (USA).

Discussion

15:00-16:30       Abstract session 2: Presentations of selected abstracts

9 ABSTRACTS (8 min presentation + 2 Discussion)

Chairs: Martina Cebova (Slovakia), Giacomo Rossitto (Italy)

15:00-15:10 –     Marta Martínez Casales: Effect of Nrf2 deletion in cardiovascular alterations associated to Ang II-induced hypertension.

15:10-15:20 –     Domenico Bagordo: Coronary flow reserve in primary aldosteronism.

15:20-15:30 –     Elvira Bragado García: Mineralocorticoid receptor antagonism prevents. inflammatory, profibrotic and osteogenic factor increase in perirenal adipose tissue of diabetic rats with chronic kidney disease.

15:30-15:40 –     Livia L Camargo: Vascular smooth muscle cell plasticity in human hypertension involves oxidative and ER stress.

15:40-15:50 –     María Cuesta-Corral: The impact of mitochondrial transplantation in cardiac damage associated with myocardial infarction.

15:50-16:00 –     Lídia Puertas-Umbert: Rolipram impacts on redox homeostasis and cell signalling in an experimental model of abdominal aortic aneurysm.

16:00-16:10 –     Oreste Lanza: Linking cardiac autonomic dysfunction, inflammation, and platelet reactivity in patients with acute coronary syndromes with or without coronary artery disease.

16:10-16:20 –     Stefano Bressa: Retinal Wall to Lumen Ratio in patients with angina and no coronary artery disease.

16:20-16:28 –     Poster Presentation: Paloma Palma Guzmán; Mineralocorticoid receptor antagonism reduces kidney damage and metalloproteinases MMP-2 and MMP-9 activities in diabetic rats with chronic kidney disease.

16:30-18.00       Session 3

Chairs: Marisol Fernandez-Alfonso (Spain), Koen Reesink (Netherlands)

(20 min each talk + 30 min general discussion)

Magnesium signaling in health and disease. Rhian M Touyz (Canada), Francisco Rios (Canada).

• Microtubule network on arterial contractility. Thomas A Jepps (Denmark).
• Angiotensinogen Suppression: A New Tool to Treat Cardiovascular and Renal Disease. Jan AH Danser (Netherlands).

18.00-18.15       Art in Science Session

18:15                    ECCR Annual business meeting – Members only

Saturday, November 25th (All times are CEST/CET)

09:00-10.30       Mindshift Network Forum

Including 6 ABSTRACTS (8 min presentation + 2 Discussion)

Chairs: Thomas Unger (Germany), Maria Christina Zennaro (France)

09:00-09:10 –     Dellaneira Setjiadi: Inappropriate Pulse Wave Velocity to Blood Pressure Level: Definition and Clinical Determinants.

09:10-09:20 –     Hala Ajjour: Assessment of dynamic Angiotensin II (Ang II) -induced calcium signals in primary human adrenocortical cells.

09:20-09:30 –     Julius Soudant: Interferon-stimulated gene 15 (ISG15) deletion protects against aldosterone-induced hypertension, cardiovascular and renal damage.

09:30-09:40 –     Ngoc Uyen Tran: Mitigating the effects of accelerated vascular ageing in hypertension.

09:40-09:50 –     Maryam Jadoon: Radiomics feature extraction for B-mode and radiofrequency images of the carotid arterial wall: a feasibility study

09:50-10:00 –     Nicolo’ Faedda: Vascular and hormonal interactions in primary aldosteronism.

10:00-10:30 –     Discussion and Forum activity

10:30-12:30       Abstract Poster session 1: Presentations of selected abstracts

11 ABSTRACTS (6 min presentation + 2 Discussion)

Chairs: Ana M Briones (Spain), Christian Delles (UK)

10:30-10:38 –     Giuseppe Palmieri: The impact of sex and dialytic age on sympathetic nervous system activation and cardiovascular risk in patients on chronic dialytic treatment.

10:38-10:46 –     Clement Byiringiro: Effects of Macrolides on Vascular Cells and Blood Pressure Control.

10:46-10:54 –     Gianluca Baldini: May Measure Month 2022 in Italy: Results of a Nationwide Survey.

10:54-11:02-      Domenico Bagordo: Coronary sinus diameter to estimate congestion predict survival.

11:02-11:10 –     Carme Ballester-Servera: Lysyl oxidase induced oxidative stress in calcific aortic valve disease and in atherosclerosis-associated calcification.

11:10-11:18 –     Matteo Lemoli: Microcirculation and SARS-CoV2 infection: a follow up study.

11:18-11:26 – Zoe González-Carnicero: TLR4 is involved in IL-1β-induced effects. Role of Nrf2.

11:26-12:04 –     Alice Bongrani: The lipolytic effect of zinc-alfa2-glycoprotein (ZAG) is related to its antioxidant activity: possible influence of glycosilation pattern.

12:04-12:12 –     Luigi Marzano: SOPRANO Study Unveils Clinical and Biochemical Outcomes Post-Adrenalectomy for Primary Aldosteronism in Reference Centers.

12:12-12:20 – Maria Fernanda Fussi: Sex differences in the response to ischemic acute kidney injury and C21 nephroprotection.

12:20-12:28 – Martina Cebova: Effect of the Nitric Oxide Donor Nicorandil on Biochemical Parameters After Experimentally Induced Myocardial Infarction.

 12:30: 13.00      Interlude

 13:00-14.15       Abstract Poster session 2: Presentations of selected abstracts

9 ABSTRACTS (6 min presentation + 2 Discussion)

Chairs: Marta Gil-Ortega, (Spain) Francisco Rios (Canada)

13:00-13:08 – Muhammad Saad Salman: Dietary sodium over the adult lifecourse and cardiac remodelling.

13:08-13:16 –     Raquel Delgado Sarafian: Putative role of Notch3 in Brown and White Adipose Tissue.

13:16-13:24 – Raisa Brito Santos: Voluntary exercise exacerbates the fibrosis in the kidney induced by folic acid in male C57BL/6J mice.

13:24-13:32 – Rita Ribeiro-Oliveira:  Angiotensin-converting enzyme inhibitory activity elicited by brewing peptides: influence of the oral route and vascular microenvironment.

13:32-13:40 – S. Ruvira: Alterations in mesenteric resistance artery function in females exposed to fetal undernutrition.

13:40-13:48 – Safiya Abdi Shugri Ahmed: Investigations on the molecular interactions of angiotensin-(1-5) with the angiotensin AT2-receptor for receptor activation.

13:48-13:56 – Sara Jiménez-González: The interaction between Galectin-3 and endoplasmic reticulum stress mediates the cardiac alterations associated with myocardial infarction in obese rats.

13:56-14:04 – V. López-Miranda: Effect of TLR4 blockade on cardio-metabolic and renal alterations caused by diet induced metabolic syndrome. Modulation of the TLR4/MYD88/NLRP3 axis expression.

14:04-14:12 – Alejandro Montoro-Garrido: The use of mitochondrial transplantation on the management of renal complications associated with cardiorenal syndrome.

 14:15-15:45       Session 4

Chairs: Christian Delles (UK),  Carmine Savoia (Italy)

(20 min each talk + 30 min general discussion)

• Oxidative stress in hypertension and cardiovascular disease. Augusto Montezano (Canada).
• Inflammatory Signature of Human Hypertension: From Regulatory to Exhausted T Cells. Tomasz T Guzik (UK).
• Hypertension, Immune system, Neurovascular Dysfunction, and Cognitive Impairment. Lorenzo Carnevale (Italy).

Discussion

15:45-16:15       Key point lecture

Introduction: Carmine Savoia (Italy)

Cardiovascular research and publishing in the era of AI. Michael Ryan (USA).

16:15-16:30       Closing remarks.

 Supported by:

We are pleased to announce that Clinical Science is working in partnership with the ECCR to host a call for papers from the 2023 annual ECCR meeting. Clinical Science is a high-impact journal linking basic science to disease mechanisms, which underscores the translational scope of the journal focused on publishing science that advances our understanding of disease pathophysiology, with cardiovascular research at its core.

Submit your full original research and reviews to Clinical Science before 30 June 2024, and published papers will be promoted as a collection highlighting the research presented and discussed at this year’s ECCR meeting. Clinical Science is published by Portland Press on behalf of the Biochemical Society and is led by Editor-in-Chief Michael J. Ryan. Publishing with Clinical Science is completely free under a standard license, and there are no page fees, publication charges or colour fees. You can choose to make your article available under an open access license, and more information on article publishing charges can be found on the journal’s website. Authors at participating institutions can publish open access with no author-facing open access fees, through our transformative Read & Publish offerings. Find out more and see the full list of participating institutions.